Isoniazid or isonicotinyl hydrazine (INH) is a first-line antibiotic used for the treatment of tuberculosis…
Pharmaceutical Microbiology
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Chloramphenicol is a protein synthesis inhibitor but the antibiotic unlike other drugs that interfere with…
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Antibiotic Resistance / Antimicrobial Resistance (AMR)Antimicrobial Agents & AntibioticsPharmaceutical Microbiology
MECHANISMS OF TRANSFER OF RESISTANCE GENES IN BACTERIA
by DrChika Below are some of the major ways through which bacteria pass on their antibiotic…
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Antibiotic Resistance / Antimicrobial Resistance (AMR)Antimicrobial Agents & AntibioticsPharmaceutical Microbiology
GENETIC BASIS OF ANTIBIOTIC RESISTANCE
by DrChikaGenetic resistance of microbes to antibiotics is due to a chromosomal mutation in the bacterial…
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Antibiotic Resistance / Antimicrobial Resistance (AMR)Antimicrobial Susceptibility Testing (AST) & AntibiogramMicrobe LabPharmaceutical Microbiology
METALLO-β-LACTAMASE (MBL) – detection methods
by DrChikaMetallo-beta-lactamases (MBLs) are beta-lactamase enzymes produced by pathogenic bacteria, and which hydrolyzes the carbapenems (e.g.…
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Antibiotic Resistance / Antimicrobial Resistance (AMR)Antimicrobial Susceptibility Testing (AST) & AntibiogramMicrobe LabPharmaceutical Microbiology
EXTENDED SPECTRUM β-LACTAMASE (ESBL) – detection methods
by DrChikaExtended spectrum beta-lactamases (ESBLs) are beta-lactamase enzymes that breakdown or hydrolyze broad-spectrum beta-lactam drugs especially…
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Pharmaceutical MicrobiologyAntimicrobial Agents & Antibiotics
ANTIMICROBIAL PROPERTIES OF LICHEN SECONDARY METABOLITES
by DrChikaLichens possess varying antimicrobial properties; and they have been shown to be active against a…
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Antibiotic Resistance / Antimicrobial Resistance (AMR)Pharmaceutical Microbiology
Materials from the iAMR team for teaching & illustrating AMR
by DrChikaAre you looking for more information about Antibiotic Resistance or antimicrobial resistance (AMR)? Do you…
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Antibiotic Resistance / Antimicrobial Resistance (AMR)Antimicrobial Susceptibility Testing (AST) & AntibiogramPharmaceutical Microbiology
BETA-LACTAMASE: an important resistance mechanism in bacteria
by DrChikaBeta-lactamases are enzymes secreted by both Gram positive and Gram negative bacteria, and which have…
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Antibiotic Resistance / Antimicrobial Resistance (AMR)Antimicrobial Susceptibility Testing (AST) & AntibiogramPharmaceutical Microbiology
MULTIDRUG RESISTANT BACTERIA (MDRB)
by DrChikaThe introduction of antibiotics into clinical medicine for the treatment of infectious diseases heralded an…