SIGNIFICANCE OF MONOCLONAL AND POLYCLONAL ANTIBODIES

The two basic forms in which antibodies can be produced in purified forms in the laboratory are as monoclonal antibodies and polyclonal antibodies. Monoclonal antibodies are homogenous antibodies produced in the laboratory by a single clone of cells (known as hybridoma cells), and all of which exhibit the same antigenic specificity. Hybridomas are cells capable […]

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Immunology & Immune System, ,

How to write a COVER LETTER – Faculty, Postgraduate, Postdoc – sample attached

How to write a COVER LETTER – Faculty, Postgraduate, Postdoc – sample attached A cover letter is a communication that you write and attach to your curriculum vitae (CV) when applying for a faculty, postgraduate or postdoctoral positions in research institutions or universities or other institutions of higher learning. The cover letter is usually a

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ORGANS OF THE IMMUNE SYSTEM AND THEIR FUNCTION

The organs of the immune system are generally divided into two major groups which are the primary lymphoid organs and the secondary lymphoid organs. The bone marrow, spleen, thymus, Peyer’s patches, liver, the tonsils, the lymph nodes and several mucosal-associated lymphoid tissues (MALT) are some of the major organs or tissues that makeup the immune

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B CELL PRODUCTION

B cells are specialized type of lymphocytes that are responsible for the production of antibodies or immunoglobulins that act as effector molecules to stimulate the entire immune system against an invading antigen or pathogen. They are primarily responsible for the development of antibody mediated immunity (AMI) in the body; and B cells are produced in

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HEPADNAVIRIDAE FAMILY

Hepadnaviridae family consists of two viral genera which are Orthohepadnavirus (which contain viruses that infect humans and other mammals)and Avihepadnavirus (which contain viruses that infect birds); and these viruses are generally called hepadnaviruses. The viruses in this family include human hepatitis B virus, animal hepatitis viruses and duck hepatitis virus. Hepadnaviruses are spherical in shape,

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Virology, , , , , , ,

Important techniques in microbiology laboratory

DIRECT PLATE COUNTING Direct plate counting is a microbiological technique used to evaluate the actual bacterial content of a product or specimen; and it gives an estimate of viable or living cells present in a sample. It is usually carried out by plating an aliquot of the sample on solid agar medium that supports the

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Microbe Lab, Techniques in Microbiology Lab

KLEBSIELLA PNEUMONIAE

Klebsiella pneumoniae is a Gram-negative, encapsulated, lactose-fermenting, non-motile, facultative rod in the genus Klebsiella and family Enterobacteriaceae. In addition to O and H antigens, K. pneumoniae possess K antigens (that consists mainly of polysaccharides). K antigens are capsular antigens found mostly amongst members of the Enterobacteriaceae family; and in the case of K. pneumoniae, the

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Bacteriology, ,

PSEUDOMONAS AERUGINOSA

Pseudomonas aeruginosa is a non-enteric, oxidase positive, Gram-negative, motile; obligate aerobic straight or curved rod that is found in the genus Pseudomonas and family Pseudomonadaceae. They are recurrently present in small numbers as members of the normal flora in the small intestine and skin of humans especially in hospitalized patients. P. aeruginosa is the most

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