PHARMACOKINETICS & PHARMACODYNAMICS

Pharmacokinetics is simply the study of how the body reacts to therapeutic agents or drugs over a period of time. It investigates what a therapeutic agent or drug does to the body after being administered. The pharmacokinetics of a particular drug describes alterations in the absorption, distribution, metabolism and the elimination or excretion of the […]

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Pharmaceutical Microbiology, ,

DRUG INTERACTION

To be clinically effective for the treatment of infectious diseases, every drug must reach a certain level of bioavailability in vivo; and this is critical because drugs contain other constituents aside the actual portion of the medicine which is necessary to express antimicrobial action in the recipient host. The bioavailability of a drug is the

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, , , , ,

MONITORING OF WATER QUALITY 

Water quality is defined as the suitability of water to sustain various uses or processes without causing any untoward effect to its users. Several human and natural factors influences the quality of water available for many industrial and domestic applications; and thus it is vital to continuously monitor water for various uses and processes –

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Environmental & Soil Microbiology, Food Microbiology, Pharmaceutical Microbiology, , ,

ACTIVE AIR MONITORING

Active air monitoring also involve the use of settle plates or sedimentation culture plates (as is applicable in passive air sampling) and contact plates for the monitoring of air quality. It involves extracting a set volume of air within a given environment into a calibrated sampler which is then passed onto the surface on an

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Environmental & Soil Microbiology, Food Microbiology, Pharmaceutical Microbiology, , , , , ,

PASSIVE AIR MONITORING

Passive air monitoring is usually done using special type of Petri dish plates known as settle plates. These culture plates are standard Petri dishes (measuring about 90 mm in diameter) that containing appropriate culture media that are opened and exposed for a given time and then incubated to allow visible colonies to develop and be

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Environmental & Soil Microbiology, Food Microbiology, Pharmaceutical Microbiology, ,

Glass Plating Beads for spreading bacteria/fungi on culture plate

Glass Plating Beads are reusable beads which helps to spread suspensions of microorganisms (bacteria or fungi) in a culture plate even much more than a conventional spreader. They are applicable when turbid suspensions of microbial cells (fungi or bacteria) are to be spread in an culture plate for such purposes as determination of the colony

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Bacteriology, Techniques in Microbiology Lab, , , , , , , ,

FTA CARDS

The acronym FTA stands for “Flinders Technology Association”. FTA CARDS are chemically treated Whatman filter papers that are designed for the collection, preservation and shipment of biological samples including clinical and environmental samples for subsequent DNA and RNA analysis. FTA cards are cotton-based, cellulose paper containing chemicals that lyse cells or biological samples, denatures proteins,

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Public Health & Parasitic Diseases (Parasitology), Techniques in Microbiology Lab, , , ,

Assessing RNA Purity, Concentration and Integrity

The integrity, purity and concentration of the RNA so isolated should be confirmed before proceeding to the next stage of the experiment. This is critical because it will help the researcher to know the amount of RNA he or she is working with, as well as ascertain its purity and integrity. And in this way,

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Biotechnology, Molecular Microbiology, Techniques in Microbiology Lab, ,

Buruli ulcer (Mycobacterium ulcerans infection)

Key facts about Buruli ulcer Buruli ulcer, caused by Mycobacterium ulcerans, is a chronic debilitating disease that affects mainly affects the skin and sometimes bone. The organism belongs to the family of bacteria that causes tuberculosis and leprosy, which provides an opportunity for collaboration with these disease programmes. However, M. ulcerans is an environmental bacterium and produces unique toxin

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Bacteriology, , , ,