CEPHALOSPORINS

Cephalosporins are beta-lactam antibiotics that are penicillinase-resistant, and with related mode of action to the penicillins. Drugs in this category are clinical substitutes for penicillins due to the development of resistance to the later by pathogenic bacteria. Cephalosporins are classified into four (4) generations based on their spectrum of activity, side chain modifications and clinical […]

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PENICILLINS

Penicillins are beta-lactam drugs that inhibit the cross-linking of N-acetyl glucosamine (NAG) and N-acetyl muramic acid (NAM) required for the formation of peptidoglycan in bacterial cells. They are generally bacterial cell wall synthesis inhibitors. Penicillin, the first member of the penicillins is a general purpose antibiotic used in clinical medicine even till date. They specifically

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CLASSIFICATION OF ANTIBIOTICS BASED ON SPECTRUM AND MECHANISM OF ACTION

Antibiotics can also be classified into different categories depending on their mode of action and/or spectrum of activity. BETA-LACTAM ANTIBIOTICS Beta-lactam antibiotics are group of naturally-synthesized antibiotics that inhibit the synthesis of cell wall in bacteria. Some later beta-lactam drugs such as methicillin, ampicillin and amoxicillin amongst others are synthesized by chemical processes. Beta-lactam drugs

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ANTIBACTERIAL AGENTS

Antibacterial agents are specifically chemical agents that kill or inhibit the growth of pathogenic bacteria. They are generally known as antibiotics. Antibiotics are complex chemical and natural substances that are secreted by some group of microorganisms (especially fungi, protozoa and bacteria), and which have the ability to either kill or inhibit the growth of other

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology

SPECTRUM OF ACTIVITY OF ANTIMICROBIAL AGENTS

The growth of pathogenic microorganisms is usually accompanied by the synthesis of new molecules including DNA, RNA and proteins. Microorganisms also acquire nutrient molecules from their surrounding environment or growth medium as their cells multiply and divide either in vivo or in vitro. Every drug has particular target site on pathogenic microorganisms when administered; and

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Overview of antimicrobial agents (antibiotics)

Ever since their discovery some decadesago, antimicrobial agents particularly antibiotics have saved mankind from the morbidity and mortality of innumerable infectious diseases and/or pathogenic agents even till date. Irrespective of the fact that pathogenic microorganisms have developed resistance genes or traits that allow them to dodge the antimicrobial onslaught of these agents or drugs, antimicrobial

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Eugon LT SUP Medium

Eugon LT Sup is a nutritious (broth) medium for detecting and enumerating microorganisms in cosmetics. It is a highly nutritious medium used for the detection and enumeration of microorganisms in cosmetic products. Eugon LT SUP is formulated to allow a better dispersion of the test sample while neutralizing preservatives that may be present in cosmetics.

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Culture media, Environmental & Soil Microbiology, , ,

Buffered Charcoal Yeast Extract (BCYE) Agar

Buffered Charcoal Yeast Extract (BCYE) Agar is used for primary isolation and cultivation of Legionella pneumophila and other Legionella species from environmental samples and clinical specimens. BCYE Agar is an enriched medium for isolation and cultivation of Legionella species. Legionella species are aerobic, intracellular, Gram negative bacteria comprising more than 50 species and 70 serogroups that are

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Culture media, Medical Microbiology, , , , ,

Chromogenic culture media for detecting antimicrobial resistance mechanisms

Chromatic Super CAZ/AVI Chromogenic medium for detecting Ceftazidime-avibactam resistant Gram-negative bacteria. Chromatic Super CAZ/AVI is a selective and differential chromogenic medium used for screening ceftazidime-avibactam resistance in Enterobacterales and Pseudomonas aeruginosa. Chromatic Super CAZ/AVI is not intended to diagnose infection or guide therapy. Results can be interpreted after incubation for 18-24 hours. Subculture to a non-selective

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Antibiotic Resistance / Antimicrobial Resistance (AMR), Antimicrobial Agents & Antibiotics, Antimicrobial Susceptibility Testing (AST) & Antibiogram, Culture media, Microbe Lab, Pharmaceutical Microbiology, , , , , , , , , , ,

CLASSES OF ANTIBIOTICS

There are several classification/types of antibiotics today, which is based on bacterial spectrum of activity (whether broad or narrow) or type of activity exhibited by the agent (whether bactericidal or bacteriostatic). Some antibiotics are also classified based on their chemical structure. And this leaves antibiotics within a particular structural class to have similar patterns of

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Antibiotic Resistance / Antimicrobial Resistance (AMR), Antimicrobial Agents & Antibiotics, Antimicrobial Susceptibility Testing (AST) & Antibiogram, Pharmaceutical Microbiology, , ,