Overview of antimicrobial agents (antibiotics)

Ever since their discovery some decadesago, antimicrobial agents particularly antibiotics have saved mankind from the morbidity and mortality of innumerable infectious diseases and/or pathogenic agents even till date. Irrespective of the fact that pathogenic microorganisms have developed resistance genes or traits that allow them to dodge the antimicrobial onslaught of these agents or drugs, antimicrobial […]

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, , , , , , ,

HISTORY OF GENE THERAPY

The history of gene therapy techniques dates back to the early 1970s and 1980s when scientists (molecular biologists in particular) proposed the idea of using functional and therapeutic gene as medicines to treat genetic disorders in man. Though the idea received little support as at the time, gene therapy techniques is still in its experimental

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Gene Therapy Notes, , , , ,

GENE THERAPY

Gene therapy is defined as the specific genetic manipulation and modification of an organism’s genome or genes through the delivery of therapeutic DNA or genes into host cells with little or no toxicity as a way of treating an inherited genetic disease or correcting a disorderly gene. Gene therapy techniques are basically used to correct

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NITROGENOUS BASES – Purine and Pyrimidines

Genes in the DNA code for proteins; and it is the gene that directs the cell in what particular order to assemble the amino acids which eventually becomes the building blocks of protein molecules. The cell of an organism must use one nucleotide or more in the DNA to spell out or specify each of

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Biotechnology, Gene Therapy Notes, , , , , , , , , ,

Eugon LT SUP Medium

Eugon LT Sup is a nutritious (broth) medium for detecting and enumerating microorganisms in cosmetics. It is a highly nutritious medium used for the detection and enumeration of microorganisms in cosmetic products. Eugon LT SUP is formulated to allow a better dispersion of the test sample while neutralizing preservatives that may be present in cosmetics.

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Culture media, Environmental & Soil Microbiology, , ,

Buffered Charcoal Yeast Extract (BCYE) Agar

Buffered Charcoal Yeast Extract (BCYE) Agar is used for primary isolation and cultivation of Legionella pneumophila and other Legionella species from environmental samples and clinical specimens. BCYE Agar is an enriched medium for isolation and cultivation of Legionella species. Legionella species are aerobic, intracellular, Gram negative bacteria comprising more than 50 species and 70 serogroups that are

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Culture media, Medical Microbiology, , , , ,

Chromogenic culture media for detecting antimicrobial resistance mechanisms

Chromatic Super CAZ/AVI Chromogenic medium for detecting Ceftazidime-avibactam resistant Gram-negative bacteria. Chromatic Super CAZ/AVI is a selective and differential chromogenic medium used for screening ceftazidime-avibactam resistance in Enterobacterales and Pseudomonas aeruginosa. Chromatic Super CAZ/AVI is not intended to diagnose infection or guide therapy. Results can be interpreted after incubation for 18-24 hours. Subculture to a non-selective

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Antibiotic Resistance / Antimicrobial Resistance (AMR), Antimicrobial Agents & Antibiotics, Antimicrobial Susceptibility Testing (AST) & Antibiogram, Culture media, Microbe Lab, Pharmaceutical Microbiology, , , , , , , , , , ,

CLASSES OF ANTIBIOTICS

There are several classification/types of antibiotics today, which is based on bacterial spectrum of activity (whether broad or narrow) or type of activity exhibited by the agent (whether bactericidal or bacteriostatic). Some antibiotics are also classified based on their chemical structure. And this leaves antibiotics within a particular structural class to have similar patterns of

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Antibiotic Resistance / Antimicrobial Resistance (AMR), Antimicrobial Agents & Antibiotics, Antimicrobial Susceptibility Testing (AST) & Antibiogram, Pharmaceutical Microbiology, , ,

SOURCES OF ANTIBIOTICS

Before the advent of conventional medicine used in clinical medicine today for the treatment of infectious diseases, people in ancient times and even now have been using some herbal plants traditionally for centuries to combat microbes that cause diseases in man. Recently, scientists have studied and reported results that support the use of these herbal

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Antibiotic Resistance / Antimicrobial Resistance (AMR), Antimicrobial Agents & Antibiotics, Antimicrobial Susceptibility Testing (AST) & Antibiogram, Pharmaceutical Microbiology, , ,