Aside from penicillins and cephalosporins, several other β-lactam and non-β-lactam antibiotics have been developed and […]
Tag: resistance mechanisms
AmpC Enzymes (β-lactamases)
AmpC β-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the Enterobacteriaceae […]
Multidrug Resistant Bacteria (MDRB)
The discovery and clinical deployment of antibiotics transformed the management of bacterial infections and fundamentally […]
Genotypic Detection of Antibiotic Resistant Bacteria and Genes
Antibiotic or antimicrobial resistance has emerged as one of the most consequential challenges confronting modern […]
Vancomycin Resistance in Enterococci
Enterococci are Gram-positive, facultatively anaerobic bacteria that constitute an important component of the gastrointestinal microbiota […]
Ceftazidime-Imipenem Antagonism Test (CIAT)
AmpC β-lactamases are bacterial enzymes that hydrolyze several β-lactam antibiotics, thereby reducing their effectiveness against […]
Antibiotics: Definition, Characteristics, and Therapeutic Uses
There is no universally accepted definition of an antibiotic, largely because the concept has evolved […]
Antibiotic Resistance and Antimicrobial Resistance (AMR)
Antimicrobial resistance (AMR) refers to the ability of microorganisms to survive or continue multiplying despite exposure […]
