carbapenemase – Microbiology Class

Genetic Basis of Antibiotic Resistance

Antibiotic resistance is fundamentally a problem of microbial evolution in which genetic variation becomes translated […]

Metallo-beta-lactamases (MBLs) represent an important class of acquired and clinically relevant resistance determinants that compromise […]

Beta-lactamases are bacterial enzymes that catalyze the hydrolysis of the β-lactam ring of β-lactam antibiotics, […]

Antimicrobial resistance (AMR), particularly antibiotic resistance, has emerged as one of the most consequential challenges […]

Extended-spectrum beta-lactamases (ESBLs) are bacterial enzymes that hydrolyze a broad range of beta-lactam antibiotics, particularly […]

AmpC β-lactamases are bacterial enzymes that hydrolyze several β-lactam antibiotics, thereby reducing their effectiveness against […]