FDA Approves First Gene Therapies to Treat Patients with Sickle Cell Disease

Today, the U.S. Food and Drug Administration approved two milestone treatments, Casgevy and Lyfgenia, representing the first cell-based gene therapies for the treatment of sickle cell disease (SCD) in patients 12 years and older. Additionally, one of these therapies, Casgevy, is the first FDA-approved treatment to utilize a type of novel genome editing technology, signaling

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Gene Therapy Notes, , ,

MEASUREMENT OF DISEASE OCCURRENCE IN A POPULATION

Statistically, the measures and/or determination of disease occurrence in a given population are usually expressed practically as rates or fractions which are stated as per the number of people in the population (for example 10, 100, and 10,000). The fraction is generally expressed as a numerator (which is the number of persons with the disease)

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Epidemiology, ,

SOURCES OF INFORMATION FOR EPIDEMIOLOGICAL DATA

In describing the health status of any population, useful data (in terms of health-related issues) from members of the community are crucial to determining the disease agent, mode of transmission, key symptoms/syndrome, type of disease, control and the establishment and evaluation of interventional measures. Epidemiologist work with data and, epidemiological studies are exclusively based on

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Epidemiology,

HOW TO CREATE YOUR EUROPASS CV AND EUROPASS COVER LETTER FOR EU APPLICATIONS (JOBS, RESEARCH, EDUCATION)

When applying for a scholarship for further studies abroad (in this case the European Union countries) or for a postdoctoral position or a doctoral position, it is important that you use the required CV format to do so. EUROPASS CV is Europe´s best known CV (curriculum vitae) format for applications within the EU (European Union).

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Research & Proposal Tips & Scholarships links, , , , , ,

USES OF EPIDEMIOLOGICAL DATA

Epidemiological data has immense benefit to the health of any people as well as their standard of living as it relates to their health. Results from epidemiological studies are used for health planning and the development of tangible public health set of rules that help a particular population to evade and contain infectious disease-causing microorganisms

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Epidemiology,

DIFFERENTIAL COUNT FOR CSF

AIM: To provide information on the different white blood cells (neutrophils, basophils, eosinophils, lymphocytes, monocytes) present in the cerebrospinal fluid (CSF) specimen. MATERIAL/APPARATUS: CSF specimen, methylene blue stain, microscope, glass slide, water, Bunsen burner, inoculating loop, immersion oil. METHOD/PROCEDURE FOR DIFFERENTIAL COUNT OF CSF SAMPLE REPORTING OF THE RESULT: Report the number of the different

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Microbe Lab, Techniques in Microbiology Lab,

HAEMOCYTOMETER CELL COUNT FOR CSF SAMPLE

Cells of mammalian or prokaryotic or eukaryotic cells can be counted in the lab from samples using different kinds of counting chmabers. The neubauer counting chamber is one major type of counting chamber generally used for counting cells, manually in the microbiology laboratory. Improved neubauer counting chamber is a manual chamber or haemocytometer that allows

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Microbe Lab, Techniques in Microbiology Lab, , , , ,

TYPES OF METABOLISM

Metabolic reactions help to maintain a state of balance or equilibrium in the cell. And the energy released during these processes is used by the cell for growth and other cellular activities. The growth of microorganisms requires the polymerization of building blocks (e.g. amino acids and nucleotides) into proteins, lipids, carbohydrates and nucleic acids. These

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Microbial Physiology & Metabolism, , , , , ,