sulphonamides

SULPHONAMIDES  

  Sulphonamides or sulpha drugs are generally known as folate synthesis inhibitors because they inhibit the synthesis of folic acid, an important precursor for the synthesis of nucleic acids in pathogenic bacteria. They are antimetabolites; and antibiotics in this category include pyrimethamine, trimethoprim, sulphamethoxazole and sulphamethoxazole-trimethoprim. Sulphonamides are the largest antibiotic family that acts as […]

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, , , , , , ,

CLASSIFICATION OF ANTIBIOTICS BASED ON SPECTRUM AND MECHANISM OF ACTION

Antibiotics can also be classified into different categories depending on their mode of action and/or spectrum of activity. BETA-LACTAM ANTIBIOTICS Beta-lactam antibiotics are group of naturally-synthesized antibiotics that inhibit the synthesis of cell wall in bacteria. Some later beta-lactam drugs such as methicillin, ampicillin and amoxicillin amongst others are synthesized by chemical processes. Beta-lactam drugs

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, , , , , , ,