beta lactam agents

CEPHALOSPORINS

Cephalosporins are beta-lactam antibiotics that are penicillinase-resistant, and with related mode of action to the penicillins. Drugs in this category are clinical substitutes for penicillins due to the development of resistance to the later by pathogenic bacteria. Cephalosporins are classified into four (4) generations based on their spectrum of activity, side chain modifications and clinical […]

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, , , , , , , , ,

PENICILLINS

Penicillins are beta-lactam drugs that inhibit the cross-linking of N-acetyl glucosamine (NAG) and N-acetyl muramic acid (NAM) required for the formation of peptidoglycan in bacterial cells. They are generally bacterial cell wall synthesis inhibitors. Penicillin, the first member of the penicillins is a general purpose antibiotic used in clinical medicine even till date. They specifically

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, , , , , , , ,