METHODS USED FOR THE INACTIVATION OF VIRUSES

Several reasons exist for the inactivation of viruses I either to use them for a useful purpose such as in studying varying properties or to inactivate and attenuate their pathogenicity or virulence so that they do not cause harm to a living host including humans, animals and plants.

Some of the major reasons for inactivating viruses so that they do not become pathogenic are shown below:

• Viruses are inactivated during vaccine production so that inactivated vaccines containing killed vaccines can be produced.

• Viruses are inactivated in order to make some human consumables such as water to be safe for consumption. This is usually applied in water producing industries and water distribution companies to inactivate pathogenic viruses.

• Viruses are inactivated during the disinfection of work benches or surfaces in the laboratory, hospitals and in our homes especially when disinfectants (with putative antiviral action) are used for cleaning dirty surfaces.

• They are also inactivated during the sterilization of hospital equipment, laboratory equipment and other health supplies. Some viruses lose their virulence when they are subjected to high temperature and pressure as that obtainable during the sterilization of heat-stable materials or equipment in the hospital or laboratory.       

References

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