Laboratory Biosafety

Risk group classification of microorganisms

The great majority of microorganisms are beneficial to man, plants, animals and the environment. These microorganisms that are non-pathogenic in nature have been applied since time immemorial to produce goods and services and products that are of immense benefit to man, animals, plants and the environment. These vast numbers of non-pathogenic microorganisms are harmless to […]

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The 3 Rs (Reduction, Refinement, Replacement): Guiding Principles in the Use of Animals For Biomedical/Scientific Research

The use of laboratory animals including mice, rats, rabbits and primates for scientific/biomedical research is guided by some principles and ethical guidelines that ensure the optimum care, protection and security of animals used in scientific investigations. Animal research is a very important procedure in biomedical research through which novel drugs are tested and scientific knowledge

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RATIONALE FOR THE CONTINUED USE OF ANIMALS FOR RESEARCH

Animals including (primates, dogs, cats, rabbits, mice) are still being used to conduct scientific/biomedical research because of some of the following reasons: References Alberts B, Bray D, Johnson A, Lewis J, Raff M, Roberts K andWalter P (1998). Essential Cell Biology: An Introduction to the Molecular Biology of the Cell. Third edition. Garland Publishing Inc.,

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Issues Surrounding the Use of Animals in Scientific Research

Animals such as mice, rats, rabbits, monkeys and primates are used in biomedical research to test the efficacy and toxicity of novel drugs and vaccines prior to their general usage in humans and animals for therapeutic purposes. The use of animals to do research whose results will in turn be extrapolated to humans is hinged

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Collection and processing of various clinical samples in the microbiology lab

COLLECTION OF SPUTUM Sputum specimens are collected from patient’s suspected to have respiratory disorders example tuberculosis (TB) and pneumonia. A sterile wide – mouthed container is given to the patient to collect the sputum. Sputum passes via the pharynx and the mouth as it is being collected, and there is always a possibility of being

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Specimen Collection in Microbiology Lab

The sample collection unit is one of the most important units in the clinical microbiology laboratory because it acts as a middle man between the patients and the microbiologists working in the laboratory. The sample collection unit is largely responsible for the collection of different clinically important specimens from patients (both outgoing and in-patients), registration

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GOOD LABORATORY PRACTICE (GLP)

Good laboratory practice (GLP) is simply defined as a laboratory quality measure or protocol that is concerned with the organizational process and the conditions under which laboratory experimentations (inclusive of other non-clinical studies) are planned, performed, monitored, recorded, archived, retrieved and reported. The main goal of GLP in any medical or non-medical laboratory is to

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CLASSIFICATION OF MICROORGANISMS BASED ON HAZARDS AND LABORATORY

Pathogenic microorganisms inclusive of viruses, bacteria, and fungi portends health challenges to the general public and healthcare workers or laboratory personnel’s working with these organisms if the proper precautionary measures are not followed in the handling of these microbes. The extensive use of these organisms in research settings or hospital laboratories should be done within

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Microbiological Risk Assessment

Microbiological risk assessment (MRA) is a structured process that is used for determining the public health risk associated with biological hazards in a given environment such as water, land, cosmetics, medications, food, air etc. Risk assessment is the backbone of the general practice of biosafety in any environment. Personnel involved in assessing public health risk in

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