Penicillium

STRUCTURES OF FUNGI

The spores (conidia) are produced in dry chains from the tips of the phialides, with the youngest spore at the base of the chain (Figure 1). Penicillium is found in the soil, decaying vegetation, air and they are common contaminants on various substances. Penicillium causes food spoilage, and it colonizes leather objects. It is an […]

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Mycology, , , , , , , , , , , , , ,

ALEXANDER FLEMMING (1881-1955)

Alexander Flemming, a Scottish born physician who spent most of his time studying bacteria discovered the world’s first antibiotic “Penicillin” from the mould Penicillium notatum. Though, mankind has used a number of chemicals including herbs to treat infectious diseases since time immemorial, the astonishing discovery of penicillin (the first therapeutically used antibiotic) marked the beginning

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General Microbiology, , , , ,

PENICILLINS

Penicillins are beta-lactam drugs that inhibit the cross-linking of N-acetyl glucosamine (NAG) and N-acetyl muramic acid (NAM) required for the formation of peptidoglycan in bacterial cells. They are generally bacterial cell wall synthesis inhibitors. Penicillin, the first member of the penicillins is a general purpose antibiotic used in clinical medicine even till date. They specifically

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, , , , , , , ,