CHLORAMPHENICOL

Chloramphenicol is a protein synthesis inhibitor but the antibiotic unlike other drugs that interfere with bacterial protein biosynthesis (e.g. tetracycline and aminoglycosides) binds to the 50S ribosomal subunit of the target bacterial ribosome the same manner that macrolides (e.g. erythromycin) exhibit their antibacterial activity. Chloramphenicol and erythromycin exhibit similar modes of antibacterial action or activity […]

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, ,