transformation

MECHANISMS OF TRANSFER OF RESISTANCE GENES IN BACTERIA

  Below are some of the major ways through which bacteria pass on their antibiotic resistance genes (ARGs) to other susceptible non–resistant bacteria in their environment: TRANSDUCTION Transduction is simply defined as the transfer of genetic material (i.e. exogenous or foreign DNA molecule) between bacteria by bacteriophages (bacterial viruses). It is the transfer of DNA […]

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Antibiotic Resistance / Antimicrobial Resistance (AMR), Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, , , , , ,

STEPS INVOLVED IN TRANSFORMING BACTERIAL CELLS

There are different types of steps involved in the transformation of a bacterial cell in gene cloning techniques. Bacterial cells are transformed when they are infused with exogenous DNA from another organism, and this makes them competent enough to express the gene product (or protein) of the gene they are carrying. Usually, the exogenous DNA

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Biotechnology, Molecular Microbiology, ,

FREDERICK GRIFFITH (1879-1941)

Frederick Griffith was a British bacteriologist who performed transformation experiments that suggested that DNA was the hereditary material. His focus was on the epidemiology and pathology of bacterial pneumonia – which led him to develop the principle of bacterial transformation – which allow scientist to transform a bacterium through the introduction of exogenous DNA carrying

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General Microbiology, , , ,