synergism

Clinical and pharmacological significance of synergism, antagonism and additive effects of drugs or pharmacological compounds

The terms synergistic effect (synergism), antagonistic effect (antagonism) and additive effect are all clinical and pharmacological phrases that have clinical applications in drug administration in real life. They are also applied in research particularly in novel drug discovery, drug testing and therapeutic drug applications. Chemical reactions in chemistry happen when two compounds or more react […]

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, , , , , , ,

DRUG INTERACTION

To be clinically effective for the treatment of infectious diseases, every drug must reach a certain level of bioavailability in vivo; and this is critical because drugs contain other constituents aside the actual portion of the medicine which is necessary to express antimicrobial action in the recipient host. The bioavailability of a drug is the

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Antimicrobial Agents & Antibiotics, Pharmaceutical Microbiology, , , , ,