pyrogens

Limulus Amoebocyte Lysate (LAL) Test

The LAL test is applied in the testing of pharmaceuticals, medical devices, water, food, and air because of its high sensitivity and specificity for endotoxins of Gram negative bacteria. LAL test is used for the quality control of pharmaceutical/medical parenteral preparations. The observation that the haemolymph (blood)of the Horseshoe crab can form clot in the […]

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Food Microbiology, Pharmaceutical Microbiology, , , , , , , , , ,

PYROGEN TEST

A pyrogen is simply defined as a fever-causing (inducing) agent that includes toxins of microorganisms. The phrase “pyrogens” is derived from the Greek word “Pyros” to mean “Fire”. Pyrogens are the lipopolysaccharide (LPS) component or endotoxins of bacteria especially Gram negative organisms. They also include the cell wall components of both Gram negative and Gram

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Food Microbiology, Pharmaceutical Microbiology, , , , , , , , , , , ,