What are ESBLs?
ESBLs (extended spectrum beta-lactamases) are enzymes that mediate resistance to extended-spectrum (third generation) cephalosporins (e.g., ceftazidime, cefotaxime, and ceftriaxone) and monobactams (e.g., aztreonam) but do not affect cephamycins (e.g., cefoxitin and cefotetan) or carbapenems (e.g., meropenem or imipenem). Why should hospital laboratories and hospitals be concerned about detecting ESBL-producing bacteria? The presence of an ESBL-producing […]