silent mutation

MUTATION

Mutation is a change in the genetic make-up (or DNA) of an organism.It is an inheritable alteration in the nucleotide sequence (or genome base sequence) of a living organism. Mutation can occur in both plant and animal cells, and it can be spontaneous (i.e. natural), prompted (or artificial), or adaptive in nature. When mutation occurs, […]

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CLASSIFICATION OF MUTATION BY THEIR EFFECTS ON THE DNA MOLECULE

Based on their effects on the structural integrity of the DNA molecule, mutations can be classified as substitution, insertion, deletion, inversion, reciprocal translocation and chromosomal rearrangements. SUBSTITUTION (BASE-PAIR SUBSTITUTION) Substitution literally means the act of replacing one thing with another. When base substitution as a type of mutation occurs during DNA replication, a single base

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