MICROBIOLOGY PROJECT TOPICS

Below are some PROJECT TOPICS for your undergraduate and postgraduate (M.Sc. & Ph.D.) research studies. These project topics are only “suggestive in nature. This implies that they can be used as they are, or they can be modified and used as you so deem fit.

@ www.MicrobiologyClass.net we are interested in the academic- and self-development of our users, and that is why we have taken it upon ourselves to update on these topics from time to time, so that our users will always have free access to the project topics of their choice.

In case you have any project topic that you will like us to include to the list, please feel free to submit your suggested project topic through our email below. Our editorial team members will look at it, and add them to the list. You can also submit such “suggested project topic” through: microbiologyclassnet@gmail.com

• Physiology and ecology of the neonatal gut microbiota
• Biodegradable Polymer Degradation in Compost Environments
• The Influence of Invasive Species on Host-Associated Microbiomes 
• Impacts of bacterial associated ectomycorrhizal fungi on forest fungal and tree growth 
• Emerging pollutant transformation and reactive oxygen species formation by oxygenase enzymes in different microbiomes
• Survival and resuscitation mechanisms of desert soil bacteria
• The effect of seasonal oxygen fluctuations on aquatic microbiomes
• Microbiome-Enhanced Silicate Weathering
• Comparative Analysis of Gut Microbiomes in Chinchillas and mice for pathogen research
• Characterization of Probiotic Properties of Limosilactobacillus fermentum
• Whole-Genome Analysis of Lactobacillus johnsonii
• Effect of flouroquinolones and aminoglycosides mixtures on soil bacterial activity
• Evolution and spread of antibiotic resistant bacteria on antimicrobial surfaces in hospitals
• Determination of the single and combined effects of antibiotics on soil bacterial and fungal communities
• Characterization of PVL-positive MRSA isolates.
• Effect of Lactiplantibacillus plantarum strains on the intestinal microbiome.
• Prevalence of Enterotoxigenic Escherichia coli in children and adults.
• Isolation and characterization of entomopathogenic fungi from soil.
• Genomic analysis of hydrocarbon oxidizing sulphur bacteria.
• Investigation of the biodegrading potentials of Fervidobacteriumpennivorans.
• Effect of calcium on the genetic makeup of Gemmatimonas phototrophica.
• Modulation of Mycorrhizal colonization for improved food production.
• Isolation and characterization of novel antimicrobial compounds from endophytes.
• Isolation and characterization of novel antimicrobial compounds from lichens.
• Monitoring of wastewaters for the prevalence of SARS-CoV-2 to mitigate COVID-19 spread.
• Metagenomics to unravel novel antimicrobial resistance genes in hospital environment.
• Determination of quorum sensing and biofilm-forming capability in Pseudomonas aeruginosa isolated from door handles, sinks, beddings and floor of hospitals 
• Occurrence and serotyping of Salmonella species from blood samples of in- and out-patients
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Acinetobacter baumannii
• Prevalence and Plasmid Profile of Fluoroquinolone – Resistant Staphylococcus aureus (FQRSA) isolated from clinical samples
• Bacteriological and Physicochemical Parameters of Selected Borehole Water Sources
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Aeromonas hydrophila
• Preliminary Studies on the Antibacterial Activities of Leaf Extracts of Azadirachta indica and Psidium guajava on Methicillin and Vancomycin Resistant Staphylococcus aureus.
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Salmonella and Shigella spcecies
• Molecular Detection of Panton-Valentine Leukocidin (PVL) Toxins in Clinical Isolates of Staphylococcus aureus
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Candida auris
• Prevalence, antibiogram and Plasmid Profile of Fluoroquinolone – Resistant Staphylococcus aureus (FQRSA) isolated from poultry and abattoir samples
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Candida albicans
• Evaluation of the antibacterial activity of Parkia biglobosa, Hymenocardia acida and Zanthoxylum zanthoxyloides extracts on pathogenic Gram negative and Gram positive bacteria
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Vibrio cholerae
• Detection and antibiogram of constitutive- and inducible-clindamycin-resistance in clinical isolates of Staphylococcus aureus
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Enterococcus faecalis
• Antibacterial Activity of Adenia Cissampeloides Plant Extracts on some selected Gram positive and Gram negative bacteria
• Evaluation of the Efficacy, Quality and Safety of Hepatitis B Vaccines stored in cold-chain systems
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Listeria monocytogenes
• Phytochemical and Antimicrobial analysis of hulls and nuts of Tetracarpidium conophorum (Ukpa) on selected Gram positive and Gram negative bacteria
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Mycobacterium species
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Escherichia coli
• In Vitro Susceptibility Test of Different Clinical bacterial Isolates against first generation cephalosporins
• Determination and isolation  of the metabolites of endophytic Colletotrichum gloeosporioides isolated from leaves of Carica papaya
• Isolation and characterization of bacteria and fungi associated with the biodegradation of municipal solid waste matter
• In Vitro Susceptibility Test of Different Clinical bacterial Isolates against second generation cephalosporins
• Isolation, antibiogram and characterization of vancomycin-resistant Staphylococcus aureus from clinical bacterial isolates
• In Vitro Susceptibility Test of Different Clinical bacterial Isolates against third generation cephalosporins
• Determination of Bioethanol Production from Corncob Hydrolysed by Cellulase of Aspergillus niger Using Zymomonas mobilis and Saccharomyces cerevisiae
• In Vitro Susceptibility Test of Different Clinical bacterial Isolates against fourth generation cephalosporins
• In Vitro Susceptibility Test of Different Clinical bacterial Isolates against fifth generation cephalosporins
• Evaluation of the Efficacy, Quality and Safety of Hepatitis B Vaccines sold in the open market
• In Vitro Susceptibility Test of Different Clinical fungal Isolates against ketoconazole and nystatin
• Phenotypic detection of extended spectrum beta lactamase (ESBL)-producing Escherichia coli isolates from hospital samples
• Phenotypic detection of metallo beta lactamase (MBL)-producing Escherichia coli isolates from hospital samples
• Phenotypic detection of AmpC enzyme producing Escherichia coli isolates from hospital samples
• Phenotypic detection of ESBL producing Klebsiella pneumoniae isolates from hospital samples
• Phenotypic detection of metallo beta lactamase (MBL)-producing Klebsiella pneumoniae isolates from hospital samples
• Phenotypic detection of AmpC enzyme producing Klebsiella pneumoniae isolates from hospital samples
• Phenotypic detection of ESBL producing Pseudomonas aeruginosa isolates from hospital samples
• Phenotypic detection of metallo beta lactamase (MBL)-producing Pseudomonas aeruginosa isolates from hospital samples
• Phenotypic detection of AmpC enzyme producing Pseudomonas aeruginosa isolates from hospital samples
• Isolation of Bacillus species with antibiotic-producing ability from soil samples
• Detection of methicillin resistant Staphylococcus aureus (MRSA)isolates from clinical samples
• Phenotypic detection of vancomycin resistant Enterococcus species from clinical samples
• Detection of methicillin resistant Staphylococcus aureus (MRSA) isolates from pig dung’s
• Detection of methicillin resistant Staphylococcus aureus (MRSA) isolates from cow dung’s
• Prevalence of Schistosoma haematobium infection in a primary school
• Prevalence of Schistosoma bovis infection in abattoir houses
• Prevalence of Schistosoma bovis infection in intestinal tract of slaughtered animals
• Evolution of biocide resistance in clinical isolates of Pseudomonas aeruginosa
• PCR detection of virulence-associated genes in multidrug resistant clinical isolates of Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli
• Molecular characterization of antibiotic resistant genes in methicillin resistant Staphylococcus aureus (MRSA) isolates of clinical origin
• PCR determination of panton valentine leukocidin genes in methicillin resistant Staphylococcus aureus (MRSA) isolates
• Comparison of Cefoxitin and Oxacillin Disk Diffusion Methods for Detection of mecA-Mediated Resistance in Staphylococcus aureus
• PCR detection of mecA gene in methicillin resistant Staphylococcus aureus (MRSA) isolates
• Antimicrobial susceptibility profile of methicillin resistant coagulase negative staphylococci (CoNS) strains of hospital origin
• Antibiogram of Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli isolates recovered from ready to eat food samples
• Susceptibility profile of Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli isolates recovered from Zobo drink samples
• Antimicrobial susceptibility profile of Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli isolates recovered from Soya milk drink samples
• Prevalence of Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli isolates in marketed sachet and bottled waters
• Phenotypic Detection of Methicillin Resistance in Staphylococcus aureus by Disk Diffusion Testing and Etest
• Prevalence of methicillin resistant Staphylococcus aureus (MRSA) isolates in pig farms
• Prevalence and antimicrobial susceptibility profile of methicillin resistant Staphylococcus aureus (MRSA) isolates from cattle farms
• Detection and prevalence of methicillin resistant Staphylococcus aureus (MRSA) isolates from goat farms
• Antimicrobial susceptibility patterns and occurrence of methicillin resistant Staphylococcus aureus (MRSA) isolates in poultry farms
• Antimicrobial susceptibility profile of Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli isolates recovered from faecal samples of poultry birds
• Antimicrobial susceptibility profile of bacterial pathogens recovered from free-range birds or fowls
• Isolation of Saccharomyces cerevisiae from fresh and soured palm wine marketed in local and urban markets
• Determination of the ethanolic and methanolic extracts of the root, leaves and stem of Azadirachta indica on Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli clinical isolates 
• Determination of the ethanolic and methanolic extracts of the root, leaves and stem of Garcinia kola on Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli clinical isolates 
• Determination of the ethanolic and methanolic extracts of the root, leaves and stem of Carica papaya on Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli clinical isolates 
• Determination of the ethanolic and methanolic extracts of the root, leaves and stem of Zingiber officinale on Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli clinical isolates 
• Investigation of Schistosoma species in Pond Water Snails
• Detection of Plasmid Borne Extended Spectrum Beta Lactamase Enzymes from Blood and Urine Isolates of Gram – Negative Bacteria
• Detection of Klebsiella pneumoniae isolates Producing CTX-M-15 Extended Spectrum Beta Lactamases
• Detection of extended-spectrum β-lactamase-producing Escherichia coli isolates from suspected community acquired urinary tract infections
• Doripenem and ertapenem resistance amongst ESBL positive and AmpC positive Escherichia coli and Klebsiella pneumoniae clinical isolates.
• Detection of extended-Spectrum Βeta-Lactamase – Producing Escherichia Coli Strains of Poultry Origin
• Detection of extended-Spectrum Βeta-Lactamase – Producing Escherichia Coli Strains of abattoir Origin
• Microbiological investigation of Escherichia coli isolates from cloacal and feacal swabs of broiler chickens for AmpC enzymes and metallo beta lactamase enzymes
• Frequency and antibiogram of uropathogens isolated from Urine Samples of HIV Infected Patients
• Inhibitory effects of neem and Bitter kola leaves on selected pathogenic bacteria and fungi
• Detection of Extended Spectrum β-Lactamase Enzymes from Otitis Media Bacteria Pathogens.
• Cloacal faecal carriage and occurrence of antibiotic resistant Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa in chicken grown with and without antibiotic supplemented feed
• Evaluation of antibacterial activities of some Nigerian medicinal plants against some Gram negative resistant bacteria pathogens
• Detection of ESBL-producing Gram negative bacteria using Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry.
• Prevalence and antibiogram of Aeromonas hydrophila isolated from water samples
• Determination of the Quality of Commercial Antibacterial Discs Available in Nigerian market
• Determination of the Medicinal Efficacy of Acetone, Aqueous, Methanol and Ethanol Crude Extracts of Mangifera indica Leaf
• Phytochemical analysis and Antimicrobial Activity of Ethanolic and Methanolic Stem and Root Extracts of Cnestis ferruginea on Multidrug Resistant Bacteria of clinical origin
• Prevalence and antibiogram of Salmonella species, Shigella species and Staphylococcus aureus in retail meats
• Determination of the Microbial Contamination and prevalence of multidrug resistant bacteria of Ready-to-Eat Fried Chicken Meat
• Antimicrobial susceptibility profile of Staphylococcus aureus from Healthy School Pupils
• Antibiogram of Streptococcus pneumoniae Isolated from the Nasopharyngeal Mucosa of primary school children
• Prevalence, antibiogram and PCR detection of the virulence-associated genes of Acinetobacter baumannii
• Antifungal and antibacterial activities of Ocimum gratissimum and Gongronema latifolium leaves on Colletotrichum species
• Phytochemical analysis and Antibacterial activity of Crude Extracts from Leaves of Wonderful Kola on some selected Gram positive and Gram negative bacteria
• Antibiotic sensitivity profiles of biofilm-producing bacterial isolates from clinical and water samples
• Metagenomics to unravel novel AMR in food chain.