EXTENDED SPECTRUM β-LACTAMASE (ESBL) – detection methods
Extended spectrum beta-lactamases (ESBLs) are beta-lactamase enzymes that breakdown or hydrolyze broad-spectrum beta-lactam drugs especially the third-generation oxyimino-cephalosporins (e.g. ceftazidime, ceftriaxone and cefotaxime). There is no consensus for the actually definition of ESBLs; but the acronym “ESBL” was originally coined to reflect the expanded substrate spectrum of the earlier beta-lactamase enzymes (e.g. TEM- and SHV-enzymes). […]
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Antibiotic Resistance / Antimicrobial Resistance (AMR), Antimicrobial Susceptibility Testing (AST) & Antibiogram, Microbe Lab, Pharmaceutical Microbiology